The idea of writing about the lives of older people living with HIV for much or most of their lives would have been unthinkable in the earliest years of the pandemic. Yet we are here now because new technologies allow people living with HIV to live longer and because, as people are sexually active throughout their entire lives, they are being diagnosed in later life. As people live longer, practical and policy support for older persons and their sexual lives will be increasingly important. Authors in this volume also point out that in parts of the world, later life does not refer to being older in years. Experiences of intersectional stigma and oppression are common throughout the world. The introduction concludes by introducing the chapters that make up the volume.